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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDX2
All Species:
26.97
Human Site:
S226
Identified Species:
49.44
UniProt:
Q99626
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99626
NP_001256.2
313
33510
S226
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Chimpanzee
Pan troglodytes
XP_522747
307
33029
S220
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Rhesus Macaque
Macaca mulatta
XP_001096874
313
33566
S226
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Dog
Lupus familis
XP_543154
314
33489
S226
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Cat
Felis silvestris
Mouse
Mus musculus
P43241
311
33458
S225
L
A
A
T
L
G
L
S
E
R
Q
V
K
I
W
Rat
Rattus norvegicus
Q05095
123
14282
Q73
K
K
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
P
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519561
154
17330
N104
R
A
K
E
R
K
M
N
K
K
K
L
R
Q
Q
Chicken
Gallus gallus
Q9DEB6
260
28826
K210
K
E
R
K
V
N
K
K
K
L
Q
Q
Q
S
Q
Frog
Xenopus laevis
Q91622
263
29182
M213
R
K
V
N
K
K
K
M
Q
Q
Q
S
Q
Q
A
Zebra Danio
Brachydanio rerio
Q9YGT6
265
29507
L215
E
F
H
F
N
R
Y
L
T
R
R
R
R
I
E
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
S228
L
P
N
T
K
V
R
S
G
S
T
N
T
N
S
Fruit Fly
Dros. melanogaster
P09085
427
45708
S313
L
A
Q
T
L
S
L
S
E
R
Q
V
K
I
W
Honey Bee
Apis mellifera
XP_001122398
358
40117
S265
L
A
L
S
L
S
L
S
E
R
Q
V
K
I
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
98.4
96.1
N.A.
92.9
27.1
N.A.
36.7
50.4
47.2
23.9
26.8
27.6
31.5
N.A.
N.A.
Protein Similarity:
100
83.7
98.4
97.1
N.A.
94.5
28.7
N.A.
41.2
57.5
58.1
38.9
39.6
38.1
44.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
6.6
6.6
13.3
20
86.6
80
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
53.3
26.6
26.6
26.6
20
86.6
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
39
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
0
54
0
0
0
0
0
8
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
39
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% I
% Lys:
16
16
8
8
16
16
16
8
16
8
8
0
54
0
0
% K
% Leu:
62
0
8
0
54
0
54
8
0
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
8
8
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
16
8
8
8
8
8
16
16
77
16
16
16
16
% Q
% Arg:
16
0
8
0
8
8
8
0
0
62
8
8
16
0
0
% R
% Ser:
0
0
0
8
0
16
0
62
0
8
0
8
0
8
8
% S
% Thr:
0
0
0
54
0
0
0
0
8
0
8
0
8
0
0
% T
% Val:
0
0
8
0
8
8
0
0
0
0
0
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _